Authors:
Alponti, Leonardo H. R. [1] ; Picinini, Monize [2] ; Urquieta-Gonzalez, Ernesto A. [2] ; Correa, Arlene G. [1]
Abstract:
The Hantzsch three-component reaction is the best-known multicomponent reaction, affording dihydropyridines which have been employed therapeutically and also as visible‐light photoredox catalysts. In this work we report the application of an ultra-stable (US) Y zeolite as a promising green catalyst in the synthesis of a series of 1,4-dihydropyridines under microwave irradiation. Using the optimized reaction conditions, 21 compounds were prepared in 64-96% isolated yields. The recovery and recycle of the USY zeolite are also reported as well as its fully characterization.
1 Centre of Excellence for Research in Sustainable Chemistry, Department of Chemistry, Brazil
2 Department of Chemical Engineering, Federal University of São Carlos, 13565-905 São Carlos, SP – Brazil
Link to article: https://www.sciencedirect.com/science/article/abs/pii/S0022286020317452?via%3Dihub
