Pesquisa

All Nobel Price awarded

ter, 04 jun 2019

Publicado por

Authors:

Ferreira Santos, Natacha Carvalho 1 ;  Valli, Marilia 2 ;  Bolzani, Vanderlan da Silva 2


Abstract:

Women have achieved great advances standing up for themselves in the last 100 years. Many important women were essential for the development of science but only a few (5 % from  total awarded individuals) have won Nobel prizes for their work. In this brief contribution, we would like to show that gender equality is in process and highlight the gaps that still have to be addressed. We also give an overview of the Brazilian scenario on this matter. In many  countries, such as Brazil, women are already half of the researchers in Chemistry, but their representation become scarcer as their career advances, in coordination and direction positions.


1  National Council for Scientific and Technological Development (CNPq), Brasilia – DF, Brazil

2   Nucleus of Bioassays, Biosynthesis and Ecophysiology of Natural Products (NuBBE), Department of Organic Chemistry, Institute of Chemistry, Sao Paulo State University (UNESP), Araraquara – SP, Brazil


Link to article:   https://www.degruyter.com/view/j/pac.2019.91.issue-4/pac-2018-1002/pac-2018-1002.xml

Indoline Synthesis

ter, 04 jun 2019

Publicado por

Authors:             

Silva, Thiago S. 1 ;  Rodrigues, Jr., Manoel T. 1 ;  Santos, Hugo 1 ;  Zeoly, Lucas A. 1 ;  Almeida, Wanda P. 2 ;  Barcelos, Rosimeire C. 3 ;  Gomes, Ralph C. 1 ; Fernandes, Fabio S. 1 ;  Coelho, Fernando 1


Abstract:

Indoline is an important structural motif present in several biologically active compounds from both natural and synthetic origins. The occurrence of this heterocyclic unity in these compounds is closely related to the biological activities they exhibit. This fact stimulated efforts that have been made worldwide to develop new synthetic approaches to prepare indolines. In this paper we reviewed critically the methods for indoline synthesis developed in the last years (from 2010 to 2018).


1  Laboratory of Synthesis of Natural Products and Drugs, Institute of Chemistry, University of Campinas, PO Box 6154, 13083-970, Campinas, SP, Brazil

2  Faculty of Pharmaceutical Sciences, University of Campinas, Rua Cândido Portinari, 200, 13083-971, Campinas, SP, Brazil

3  Instituto Federal de Ciência, Tecnologia e Educação de Minas Gerais, Belo Horizonte, MG, Brazil


Link to article:  https://www.sciencedirect.com/science/article/pii/S0040402019301449?via%3Dihub